From the A14 Motorway (Bologna – Taranto): south exit “Ascoli Piceno – San Benedetto del Tronto” or north exit “Grottammare”.
From Rome: take the A24 Motorway (Roma – L’Aquila) to its end in Teramo; then head to Giulianova and enter the A14 Motorway (Bologna – Taranto). Exit at “Ascoli Piceno – San Benedetto del Tronto”.
From Florence: take “Val di Chiana” exit (A1 motorway) and then the highway to Perugia – Foligno, Muccia, Macerata – Civitanova Marche. At Civitanova M. enter the A14 and exit at “San Benedetto del Tronto”.
There are a lot of train links to S. Benedetto from Milano – Bologna – Ancona (north) or Lecce from south (info at Trenitalia official site)
San Benedetto is only 90 kilometres from:
Ancona (1 hour drive from San Benedetto del Tronto) is the nearest port with scheduled departures to Croatia, Greece, Turkey, Cipro and Israel..
San Benedetto is connected to all major Italian and European cities through daily bus services. Info at: Autolinee Cardinali, Gaspari Bus s.r.l., Roma Marche linee s.p.a., Start spa (Rome and Naples); Baltour (Italy and Europe), Flixbus.